
Episode Summary
What does it take to build world class AI companies out of Australia, and why does San Francisco still move 6 to 9 months faster? In this episode, Brendan sits down with three of the most ambitious technical founders in the country: Pasha Rayan (CEO & Co-Founder at A1Base), Anshul J. (Co-Founder at Everlab) and Jacky Koh (Founder at Relevance AI).
They break down the rise of agentic AI, how engineering culture in SF accelerates innovation, and why the next generation of founders need to think in $100B outcomes. They dive into everything from 10 to 20 times engineering productivity gains, to building autonomous healthcare, to creating the communication layer for AI coworkers that everyday people will talk to like friends.
They also unpack what Australia must do to stay competitive, how to build teams that love hard problems, and why ambition, pace and hands-on founders matter more than ever. It’s a rare inside look at the operators defining the next era of AI infrastructure, agent orchestration and human health.
If you want to understand where AI agents are really going, and how Australia can catch up to the frontier, get subscribed.
Chapters:
00:00 Intro and Founder Backgrounds
02:25 SF vs Australia: The 6 to 9 Month AI Gap
05:00 The 10 to 20 Times Engineering Productivity Unlock
08:20 How Founders Use AI Agents Inside Their Companies
10:54 What Twilio for AI Agents Really Means
12:39 Making AI Agents Relatable for Everyday People
15:45 Culture, Ambition and the Australian Mindset
19:37 Autonomous Healthcare: What AI Doctors Actually Look Like
22:18 The $100B Ambition Mindset
31:33 Why Hard Problems Create Real Moats
33:32 Inside Everlab’s Massive Seed Round
36:57 The Craziest AI Pitches Right Now
40:51 Predicting the Next Big Wave in AI and Agents
45:46 Inside Relevance AI’s Series B with Bessemer
48:24 Should AI Startups Delay Revenue?
52:10 How A1 Base Is Building the Future of AI Communication
55:14 How Everlab Scales Doctors and Real World Ops
59:55 Going Global: Cracking the US Market
01:06:41 Should Aussie Founders Move to the US Earlier?
01:10:55 The Next Agentic Trends You Haven’t Heard Yet
01:14:48 What AI Adoption Will Look Like in the Next Year
01:16:53 Why Engineers Should Join These Startups
01:21:00 Closing + Canva Guest Tease






