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S3 | E6 Anton Jackson Smith (Founder of b.next) on building synthetic cells, programmable biology, and the future of biotech

11 April 2025

Imagine if you built a car and every time you took it out of the garage, something had changed just overnight. That's biology right now.
Anton Jackson Smith
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Anton Jackson Smith is a synthetic biologist, Stanford PhD, and founder of b.next, a startup building synthetic cells from scratch to make biology truly programmable. Think of it as rewriting life’s codebase, with applications ranging from cancer treatments and diagnostics to lab-grown foods and smart crops. In today’s episode, Anton breaks down what synthetic cells actually are (and why they matter), how his open-source platform Nucleus is changing the way biology is engineered, and why the future of medicine, agriculture, and climate tech might be written in DNA. We also dig into his journey, from coding in Queenstown and law school in Otago, to cutting-edge research in Silicon Valley, and how a random article on programmable E. coli changed everything. In this conversation, we cover: • How synthetic cells could power the next generation of therapeutics and diagnostics • Why biology needs its own “AWS moment” and how open source can unlock it • The real business model behind synthetic biology (and why it's not just science) • How Kiwi strengths in agriculture and biotech could shape a global future • What New Zealand needs to do to retain and return its brightest minds Anton also shares his vision for a safer, more ethical bio-economy, and how we can build powerful new tools without repeating the mistakes of the past.

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🙋🏻‍♂️ Anton Jackson Smith on LinkedIn: https://www.linkedin.com/in/antonjacksonsmith

🧬 B Next Bio: https://www.bnext.bio

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